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SMILES: Cc1nc2cc(ccc2o1)N=C(NC#N)N[C@H]1CCCCN(CC(=O)N2CCCC2)C1=O

InChI Key: InChIKey=CCZONHPFHPWFBE-KRWDZBQOSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50296262   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))		BDBM50296262
PNG
((S)-2-cyano-1-(2-methylbenzo[d]oxazol-5-yl)-3-(2-o...)
Show SMILES Cc1nc2cc(ccc2o1)N=C(NC#N)N[C@H]1CCCCN(CC(=O)N2CCCC2)C1=O |r,w:10.11|
Show InChI InChI=1S/C22H27N7O3/c1-15-25-18-12-16(7-8-19(18)32-15)26-22(24-14-23)27-17-6-2-3-11-29(21(17)31)13-20(30)28-9-4-5-10-28/h7-8,12,17H,2-6,9-11,13H2,1H3,(H2,24,26,27)/t17-/m0/s1
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Article
PubMed
n/an/a 2.68E+3n/an/an/an/an/an/a



Bristol-Myers Squibb Company

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a-mediated cleavage of synthetic substrate S-2222

Bioorg Med Chem Lett 19: 4034-41 (2009)


Article DOI: 10.1016/j.bmcl.2009.06.014
BindingDB Entry DOI: 10.7270/Q2TQ61KM
More data for this
Ligand-Target Pair