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SMILES: Cc1nc2ccc(cc2[nH]1)N=C(NC#N)N[C@H]1CCCCN(CC(=O)N2CCCC2)C1=O

InChI Key: InChIKey=GESZKJNRBVKRKT-SFHVURJKSA-N

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50296265   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))		BDBM50296265
PNG
((S)-2-cyano-1-(2-methyl-1H-benzo[d]imidazol-5-yl)-...)
Show SMILES Cc1nc2ccc(cc2[nH]1)N=C(NC#N)N[C@H]1CCCCN(CC(=O)N2CCCC2)C1=O |r,w:10.11|
Show InChI InChI=1S/C22H28N8O2/c1-15-25-17-8-7-16(12-19(17)26-15)27-22(24-14-23)28-18-6-2-3-11-30(21(18)32)13-20(31)29-9-4-5-10-29/h7-8,12,18H,2-6,9-11,13H2,1H3,(H,25,26)(H2,24,27,28)/t18-/m0/s1
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n/an/a 1.19E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a-mediated cleavage of synthetic substrate S-2222

Bioorg Med Chem Lett 19: 4034-41 (2009)


Article DOI: 10.1016/j.bmcl.2009.06.014
BindingDB Entry DOI: 10.7270/Q2TQ61KM
More data for this
Ligand-Target Pair