BDBM50296276 (S)-2-cyano-1-(6-fluoro-2-methylbenzofuran-5-yl)-3-(2-oxo-1-(2-oxo-2-(pyrrolidin-1-yl)ethyl)azepan-3-yl)guanidine::CHEMBL565082
SMILES: Cc1cc2cc(N=C(NC#N)N[C@H]3CCCCN(CC(=O)N4CCCC4)C3=O)c(F)cc2o1
InChI Key: InChIKey=PRNVOMBXRFOTSF-SFHVURJKSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Coagulation factor X (Homo sapiens (Human)) | BDBM50296276 ((S)-2-cyano-1-(6-fluoro-2-methylbenzofuran-5-yl)-3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 76 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company Curated by ChEMBL | Assay Description Inhibition of human factor 10a-mediated cleavage of synthetic substrate S-2222 | Bioorg Med Chem Lett 19: 4034-41 (2009) Article DOI: 10.1016/j.bmcl.2009.06.014 BindingDB Entry DOI: 10.7270/Q2TQ61KM | |||||||||||
More data for this Ligand-Target Pair |