BDBM50296277 (S)-1-(7-chloro-2-methylbenzofuran-5-yl)-2-cyano-3-(2-oxo-1-(2-oxo-2-(pyrrolidin-1-yl)ethyl)azepan-3-yl)guanidine::CHEMBL556896

SMILES: Cc1cc2cc(cc(Cl)c2o1)N=C(NC#N)N[C@H]1CCCCN(CC(=O)N2CCCC2)C1=O

InChI Key: InChIKey=ZZHYPLWGYBAHCD-IBGZPJMESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50296277   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50296277 ((S)-1-(7-chloro-2-methylbenzofuran-5-yl)-2-cyano-3...) Show SMILES Cc1cc2cc(cc(Cl)c2o1)N=C(NC#N)N[C@H]1CCCCN(CC(=O)N2CCCC2)C1=O |r,w:11.12| Show InChI InChI=1S/C23H27ClN6O3/c1-15-10-16-11-17(12-18(24)21(16)33-15)27-23(26-14-25)28-19-6-2-3-9-30(22(19)32)13-20(31)29-7-4-5-8-29/h10-12,19H,2-9,13H2,1H3,(H2,26,27,28)/t19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of human factor 10a-mediated cleavage of synthetic substrate S-2222				Bioorg Med Chem Lett 19: 4034-41 (2009) Article DOI: 10.1016/j.bmcl.2009.06.014 BindingDB Entry DOI: 10.7270/Q2TQ61KM
					More data for this Ligand-Target Pair