BDBM50296278 (S)-2-cyano-1-(2,7-dimethylbenzofuran-5-yl)-3-(2-oxo-1-(2-oxo-2-(pyrrolidin-1-yl)ethyl)azepan-3-yl)guanidine::CHEMBL560255

SMILES: Cc1cc2cc(cc(C)c2o1)N=C(NC#N)N[C@H]1CCCCN(CC(=O)N2CCCC2)C1=O

InChI Key: InChIKey=YHTZPOXDQYMATN-FQEVSTJZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50296278   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50296278 ((S)-2-cyano-1-(2,7-dimethylbenzofuran-5-yl)-3-(2-o...) Show SMILES Cc1cc2cc(cc(C)c2o1)N=C(NC#N)N[C@H]1CCCCN(CC(=O)N2CCCC2)C1=O |r,w:11.12| Show InChI InChI=1S/C24H30N6O3/c1-16-11-19(13-18-12-17(2)33-22(16)18)27-24(26-15-25)28-20-7-3-4-10-30(23(20)32)14-21(31)29-8-5-6-9-29/h11-13,20H,3-10,14H2,1-2H3,(H2,26,27,28)/t20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of human factor 10a-mediated cleavage of synthetic substrate S-2222				Bioorg Med Chem Lett 19: 4034-41 (2009) Article DOI: 10.1016/j.bmcl.2009.06.014 BindingDB Entry DOI: 10.7270/Q2TQ61KM
					More data for this Ligand-Target Pair