BDBM50296282 (R)-2-cyano-1-(2-methylbenzofuran-5-yl)-3-(2-oxo-1-(2-oxo-2-(pyrrolidin-1-yl)ethyl)pyrrolidin-3-yl)guanidine::CHEMBL563794

SMILES: Cc1cc2cc(ccc2o1)N=C(NC#N)N[C@@H]1CCN(CC(=O)N2CCCC2)C1=O

InChI Key: InChIKey=MNMRIPXOAVTNOQ-QGZVFWFLSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50296282   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50296282 ((R)-2-cyano-1-(2-methylbenzofuran-5-yl)-3-(2-oxo-1...) Show SMILES Cc1cc2cc(ccc2o1)N=C(NC#N)N[C@@H]1CCN(CC(=O)N2CCCC2)C1=O |r,w:10.11| Show InChI InChI=1S/C21H24N6O3/c1-14-10-15-11-16(4-5-18(15)30-14)24-21(23-13-22)25-17-6-9-27(20(17)29)12-19(28)26-7-2-3-8-26/h4-5,10-11,17H,2-3,6-9,12H2,1H3,(H2,23,24,25)/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of human factor 10a-mediated cleavage of synthetic substrate S-2222				Bioorg Med Chem Lett 19: 4034-41 (2009) Article DOI: 10.1016/j.bmcl.2009.06.014 BindingDB Entry DOI: 10.7270/Q2TQ61KM
					More data for this Ligand-Target Pair