BDBM50296288 1-((3S)-1-(2-(3-benzylpyrrolidin-1-yl)-2-oxoethyl)-2-oxoazepan-3-yl)-2-cyano-3-(2-methylbenzofuran-5-yl)guanidine::CHEMBL562316

SMILES: Cc1cc2cc(ccc2o1)N=C(NC#N)N[C@H]1CCCCN(CC(=O)N2CCC(Cc3ccccc3)C2)C1=O

InChI Key: InChIKey=FMKJSHFGRWLZHV-NASUQTAISA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50296288   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50296288 (1-((3S)-1-(2-(3-benzylpyrrolidin-1-yl)-2-oxoethyl)...) Show SMILES Cc1cc2cc(ccc2o1)N=C(NC#N)N[C@H]1CCCCN(CC(=O)N2CCC(Cc3ccccc3)C2)C1=O |r,w:10.11| Show InChI InChI=1S/C30H34N6O3/c1-21-15-24-17-25(10-11-27(24)39-21)33-30(32-20-31)34-26-9-5-6-13-36(29(26)38)19-28(37)35-14-12-23(18-35)16-22-7-3-2-4-8-22/h2-4,7-8,10-11,15,17,23,26H,5-6,9,12-14,16,18-19H2,1H3,(H2,32,33,34)/t23?,26-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of human factor 10a-mediated cleavage of synthetic substrate S-2222				Bioorg Med Chem Lett 19: 4034-41 (2009) Article DOI: 10.1016/j.bmcl.2009.06.014 BindingDB Entry DOI: 10.7270/Q2TQ61KM
					More data for this Ligand-Target Pair