BDBM50296428 2-(2-methoxyphenyl)-N-(5-(4-methoxyphenyl)-1,3,4-thiadiazol-2-yl)-N-propylacetamide::CHEMBL549506

SMILES: CCCN(C(=O)Cc1ccccc1OC)c1nnc(s1)-c1ccc(OC)cc1

InChI Key: InChIKey=NTIDDHDYECNRFW-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50296428   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carboxypeptidase B (Helicoverpa zea (Corn earworm moth) (Heliothis zea...)	BDBM50296428 (2-(2-methoxyphenyl)-N-(5-(4-methoxyphenyl)-1,3,4-t...) Show SMILES CCCN(C(=O)Cc1ccccc1OC)c1nnc(s1)-c1ccc(OC)cc1 Show InChI InChI=1S/C21H23N3O3S/c1-4-13-24(19(25)14-16-7-5-6-8-18(16)27-3)21-23-22-20(28-21)15-9-11-17(26-2)12-10-15/h5-12H,4,13-14H2,1-3H3	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.97E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universitat Aut£noma de Barcelona Curated by ChEMBL					Assay Description Inhibition of corn earworm recombinant carboxypeptidase B expressed in Pichia pastoris system				Eur J Med Chem 44: 3266-71 (2009) Article DOI: 10.1016/j.ejmech.2009.03.034 BindingDB Entry DOI: 10.7270/Q26110C4
					More data for this Ligand-Target Pair
Thrombin-activatable fibrinolysis (TAFI) (Homo sapiens (Human))	BDBM50296428 (2-(2-methoxyphenyl)-N-(5-(4-methoxyphenyl)-1,3,4-t...) Show SMILES CCCN(C(=O)Cc1ccccc1OC)c1nnc(s1)-c1ccc(OC)cc1 Show InChI InChI=1S/C21H23N3O3S/c1-4-13-24(19(25)14-16-7-5-6-8-18(16)27-3)21-23-22-20(28-21)15-9-11-17(26-2)12-10-15/h5-12H,4,13-14H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.51E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universitat Aut£noma de Barcelona Curated by ChEMBL					Assay Description Inhibition of human recombinant carboxypeptidase B expressed in Pichia pastoris system				Eur J Med Chem 44: 3266-71 (2009) Article DOI: 10.1016/j.ejmech.2009.03.034 BindingDB Entry DOI: 10.7270/Q26110C4
					More data for this Ligand-Target Pair
Carboxypeptidase A1 (Bos taurus (bovine))	BDBM50296428 (2-(2-methoxyphenyl)-N-(5-(4-methoxyphenyl)-1,3,4-t...) Show SMILES CCCN(C(=O)Cc1ccccc1OC)c1nnc(s1)-c1ccc(OC)cc1 Show InChI InChI=1S/C21H23N3O3S/c1-4-13-24(19(25)14-16-7-5-6-8-18(16)27-3)21-23-22-20(28-21)15-9-11-17(26-2)12-10-15/h5-12H,4,13-14H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.28E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universitat Aut£noma de Barcelona Curated by ChEMBL					Assay Description Inhibition of bovine carboxypeptidase A1				Eur J Med Chem 44: 3266-71 (2009) Article DOI: 10.1016/j.ejmech.2009.03.034 BindingDB Entry DOI: 10.7270/Q26110C4
					More data for this Ligand-Target Pair