BDBM50296548 1-(2-(diethylamino)ethyl)-8,9-dihydro-3H-pyrrolo[3,2-f]isoquinolin-6(7H)-one::CHEMBL564183

SMILES: CCN(CC)CCc1c[nH]c2ccc3C(=O)NCCc3c12

InChI Key: InChIKey=ACRUSVKWMVZJFM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50296548   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50296548 (1-(2-(diethylamino)ethyl)-8,9-dihydro-3H-pyrrolo[3...) Show SMILES CCN(CC)CCc1c[nH]c2ccc3C(=O)NCCc3c12 Show InChI InChI=1S/C17H23N3O/c1-3-20(4-2)10-8-12-11-19-15-6-5-14-13(16(12)15)7-9-18-17(14)21/h5-6,11,19H,3-4,7-10H2,1-2H3,(H,18,21)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
IRBM--Merck Research Laboratories Rome Curated by ChEMBL					Assay Description Inhibition of PARP1 in human HeLa cells by microplate scintillation counting				Bioorg Med Chem Lett 19: 4042-5 (2009) Article DOI: 10.1016/j.bmcl.2009.06.031 BindingDB Entry DOI: 10.7270/Q2WH2Q09
					More data for this Ligand-Target Pair