BDBM50296593 2-(5-(3,5-difluorophenyl)-3-(((1S,3R)-3-fluorocyclopentylamino)methyl)-4-methyl-1H-pyrazol-1-yl)ethanol::CHEMBL555354

SMILES: Cc1c(CN[C@H]2CC[C@@H](F)C2)nn(CCO)c1-c1cc(F)cc(F)c1

InChI Key: InChIKey=YECGWTLQNHYAPE-CJNGLKHVSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50296593   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50296593 (2-(5-(3,5-difluorophenyl)-3-(((1S,3R)-3-fluorocycl...) Show SMILES Cc1c(CN[C@H]2CC[C@@H](F)C2)nn(CCO)c1-c1cc(F)cc(F)c1 |r| Show InChI InChI=1S/C18H22F3N3O/c1-11-17(10-22-16-3-2-13(19)9-16)23-24(4-5-25)18(11)12-6-14(20)8-15(21)7-12/h6-8,13,16,22,25H,2-5,9-10H2,1H3/t13-,16+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr14-NC/OFQ from ORL1 receptor				Bioorg Med Chem Lett 19: 4729-32 (2009) Article DOI: 10.1016/j.bmcl.2009.06.051 BindingDB Entry DOI: 10.7270/Q2H9958F
					More data for this Ligand-Target Pair