BindingDB PrimarySearch

null

SMILES: COc1ncc(\C=C\C(=O)C23CC4CC(CC(C4)C2)C3)cc1C

InChI Key: InChIKey=QVRVLZOOVQTCDX-ONEGZZNKSA-N

Found 2 hits for monomerid = 50296676
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Metabotropic glutamate receptor 1 (RAT)	BDBM50296676 ((E)-1-Adamantan-1-yl-3-(4-methoxy-3-methyl-phenyl)...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	294	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Pharmaceuticals GmbH Curated by ChEMBL					Assay Description Displacement of [3H]E-3-(2-chloro-8-methylquinolin-3-yl)-1-(thiophen-2-yl)prop-2-en-1-one from mGluR1 in rat cerebellar membrane after 14 to 16 hrs b...				Bioorg Med Chem 17: 5708-15 (2009) Article DOI: 10.1016/j.bmc.2009.05.072 BindingDB Entry DOI: 10.7270/Q2416X30
Merz Pharmaceuticals GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50296676 ((E)-1-Adamantan-1-yl-3-(4-methoxy-3-methyl-phenyl)...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	5.15E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Pharmaceuticals GmbH Curated by ChEMBL					Assay Description Displacement of [3H]MPEP from mGluR5 in rat cortical membrane after 60 mins by liquid scintillation counting				Bioorg Med Chem 17: 5708-15 (2009) Article DOI: 10.1016/j.bmc.2009.05.072 BindingDB Entry DOI: 10.7270/Q2416X30
Merz Pharmaceuticals GmbH Curated by ChEMBL					More data for this Ligand-Target Pair