BDBM50297039 3,6-diamino-4-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile::CHEMBL564921

SMILES: Nc1n[nH]c2nc(N)c(C#N)c(-c3ccccc3)c12

InChI Key: InChIKey=CLVVBNMTYMKNAP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50297039   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent-like kinase 5 (Homo sapiens (Human))	BDBM50297039 (3,6-diamino-4-phenyl-1H-pyrazolo[3,4-b]pyridine-5-...) Show SMILES Nc1n[nH]c2nc(N)c(C#N)c(-c3ccccc3)c12 Show InChI InChI=1S/C13H10N6/c14-6-8-9(7-4-2-1-3-5-7)10-12(16)18-19-13(10)17-11(8)15/h1-5H,(H5,15,16,17,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
Laboratorio de Radicales Libres y Química Computacional (IQOG, CSIC) Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/P25 by scintillation counting				Bioorg Med Chem Lett 19: 4566-9 (2009) Article DOI: 10.1016/j.bmcl.2009.06.099 BindingDB Entry DOI: 10.7270/Q2XD11QB
					More data for this Ligand-Target Pair
Dual-specificity tyrosine-phosphorylation regulated kinase 1A (Homo sapiens (Human))	BDBM50297039 (3,6-diamino-4-phenyl-1H-pyrazolo[3,4-b]pyridine-5-...) Show SMILES Nc1n[nH]c2nc(N)c(C#N)c(-c3ccccc3)c12 Show InChI InChI=1S/C13H10N6/c14-6-8-9(7-4-2-1-3-5-7)10-12(16)18-19-13(10)17-11(8)15/h1-5H,(H5,15,16,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Laboratorio de Radicales Libres y Química Computacional (IQOG, CSIC) Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fusion DYRK1A expressed in Escherichia coli				Bioorg Med Chem Lett 19: 4566-9 (2009) Article DOI: 10.1016/j.bmcl.2009.06.099 BindingDB Entry DOI: 10.7270/Q2XD11QB
					More data for this Ligand-Target Pair