null

SMILES: Cc1c(nc2ccc(NC(=O)c3ccc(nc3)-c3ccc(F)cc3)cn12)C1CC1

InChI Key: InChIKey=UWTLHZUOMNUCCE-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50297071   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50297071 (CHEMBL562136 | N-(2-cyclopropyl-3-methylimidazo[1,...) Show SMILES Cc1c(nc2ccc(NC(=O)c3ccc(nc3)-c3ccc(F)cc3)cn12)C1CC1 Show InChI InChI=1S/C23H19FN4O/c1-14-22(16-2-3-16)27-21-11-9-19(13-28(14)21)26-23(29)17-6-10-20(25-12-17)15-4-7-18(24)8-5-15/h4-13,16H,2-3H2,1H3,(H,26,29)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	94	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human MCH1 receptor expressed in CHO cells assessed as inhibition of MCH-induced intracellular calcium level by FLIPR assay				Bioorg Med Chem Lett 19: 4589-93 (2009) Article DOI: 10.1016/j.bmcl.2009.06.101 BindingDB Entry DOI: 10.7270/Q2SN091G
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50297071 (CHEMBL562136 | N-(2-cyclopropyl-3-methylimidazo[1,...) Show SMILES Cc1c(nc2ccc(NC(=O)c3ccc(nc3)-c3ccc(F)cc3)cn12)C1CC1 Show InChI InChI=1S/C23H19FN4O/c1-14-22(16-2-3-16)27-21-11-9-19(13-28(14)21)26-23(29)17-6-10-20(25-12-17)15-4-7-18(24)8-5-15/h4-13,16H,2-3H2,1H3,(H,26,29)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCH1 receptor				Bioorg Med Chem Lett 19: 4589-93 (2009) Article DOI: 10.1016/j.bmcl.2009.06.101 BindingDB Entry DOI: 10.7270/Q2SN091G
					More data for this Ligand-Target Pair