Found 10 hits for monomerid = 50297446 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50297446
(CHEMBL561604 | N-hydroxy-7,7-bis(5-nitro-1H-indol-...)Show SMILES ONC(=O)CCCCCC(c1c[nH]c2ccc(cc12)[N+]([O-])=O)c1c[nH]c2ccc(cc12)[N+]([O-])=O Show InChI InChI=1S/C23H23N5O6/c29-23(26-30)5-3-1-2-4-16(19-12-24-21-8-6-14(27(31)32)10-17(19)21)20-13-25-22-9-7-15(28(33)34)11-18(20)22/h6-13,16,24-25,30H,1-5H2,(H,26,29) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Sigma-Tau Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human HDAC1 by fluroimetry |
Bioorg Med Chem Lett 19: 2840-3 (2009)
Checked by Author Article DOI: 10.1016/j.bmcl.2009.03.101 BindingDB Entry DOI: 10.7270/Q2PN95PT |
More data for this Ligand-Target Pair | |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM50297446
(CHEMBL561604 | N-hydroxy-7,7-bis(5-nitro-1H-indol-...)Show SMILES ONC(=O)CCCCCC(c1c[nH]c2ccc(cc12)[N+]([O-])=O)c1c[nH]c2ccc(cc12)[N+]([O-])=O Show InChI InChI=1S/C23H23N5O6/c29-23(26-30)5-3-1-2-4-16(19-12-24-21-8-6-14(27(31)32)10-17(19)21)20-13-25-22-9-7-15(28(33)34)11-18(20)22/h6-13,16,24-25,30H,1-5H2,(H,26,29) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 590 | n/a | n/a | n/a | n/a | n/a | n/a |
Sigma-Tau Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human HDAC2 by fluroimetry |
Bioorg Med Chem Lett 19: 2840-3 (2009)
Checked by Author Article DOI: 10.1016/j.bmcl.2009.03.101 BindingDB Entry DOI: 10.7270/Q2PN95PT |
More data for this Ligand-Target Pair | |
Histone deacetylase 3
(Homo sapiens (Human)) | BDBM50297446
(CHEMBL561604 | N-hydroxy-7,7-bis(5-nitro-1H-indol-...)Show SMILES ONC(=O)CCCCCC(c1c[nH]c2ccc(cc12)[N+]([O-])=O)c1c[nH]c2ccc(cc12)[N+]([O-])=O Show InChI InChI=1S/C23H23N5O6/c29-23(26-30)5-3-1-2-4-16(19-12-24-21-8-6-14(27(31)32)10-17(19)21)20-13-25-22-9-7-15(28(33)34)11-18(20)22/h6-13,16,24-25,30H,1-5H2,(H,26,29) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Sigma-Tau Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human HDAC3 by fluroimetry |
Bioorg Med Chem Lett 19: 2840-3 (2009)
Checked by Author Article DOI: 10.1016/j.bmcl.2009.03.101 BindingDB Entry DOI: 10.7270/Q2PN95PT |
More data for this Ligand-Target Pair | |
Histone deacetylase 4
(Homo sapiens (Human)) | BDBM50297446
(CHEMBL561604 | N-hydroxy-7,7-bis(5-nitro-1H-indol-...)Show SMILES ONC(=O)CCCCCC(c1c[nH]c2ccc(cc12)[N+]([O-])=O)c1c[nH]c2ccc(cc12)[N+]([O-])=O Show InChI InChI=1S/C23H23N5O6/c29-23(26-30)5-3-1-2-4-16(19-12-24-21-8-6-14(27(31)32)10-17(19)21)20-13-25-22-9-7-15(28(33)34)11-18(20)22/h6-13,16,24-25,30H,1-5H2,(H,26,29) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
Sigma-Tau Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human HDAC4 by fluroimetry |
Bioorg Med Chem Lett 19: 2840-3 (2009)
Checked by Author Article DOI: 10.1016/j.bmcl.2009.03.101 BindingDB Entry DOI: 10.7270/Q2PN95PT |
More data for this Ligand-Target Pair | |
Histone deacetylase 10
(Homo sapiens (Human)) | BDBM50297446
(CHEMBL561604 | N-hydroxy-7,7-bis(5-nitro-1H-indol-...)Show SMILES ONC(=O)CCCCCC(c1c[nH]c2ccc(cc12)[N+]([O-])=O)c1c[nH]c2ccc(cc12)[N+]([O-])=O Show InChI InChI=1S/C23H23N5O6/c29-23(26-30)5-3-1-2-4-16(19-12-24-21-8-6-14(27(31)32)10-17(19)21)20-13-25-22-9-7-15(28(33)34)11-18(20)22/h6-13,16,24-25,30H,1-5H2,(H,26,29) | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
Sigma-Tau Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human HDAC10 by fluroimetry |
Bioorg Med Chem Lett 19: 2840-3 (2009)
Checked by Author Article DOI: 10.1016/j.bmcl.2009.03.101 BindingDB Entry DOI: 10.7270/Q2PN95PT |
More data for this Ligand-Target Pair | |
Cereblon/Histone deacetylase 6
(Homo sapiens (Human)) | BDBM50297446
(CHEMBL561604 | N-hydroxy-7,7-bis(5-nitro-1H-indol-...)Show SMILES ONC(=O)CCCCCC(c1c[nH]c2ccc(cc12)[N+]([O-])=O)c1c[nH]c2ccc(cc12)[N+]([O-])=O Show InChI InChI=1S/C23H23N5O6/c29-23(26-30)5-3-1-2-4-16(19-12-24-21-8-6-14(27(31)32)10-17(19)21)20-13-25-22-9-7-15(28(33)34)11-18(20)22/h6-13,16,24-25,30H,1-5H2,(H,26,29) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Sigma-Tau Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human HDAC6 by fluroimetry |
Bioorg Med Chem Lett 19: 2840-3 (2009)
Checked by Author Article DOI: 10.1016/j.bmcl.2009.03.101 BindingDB Entry DOI: 10.7270/Q2PN95PT |
More data for this Ligand-Target Pair | |
Histone deacetylase 7
(Homo sapiens (Human)) | BDBM50297446
(CHEMBL561604 | N-hydroxy-7,7-bis(5-nitro-1H-indol-...)Show SMILES ONC(=O)CCCCCC(c1c[nH]c2ccc(cc12)[N+]([O-])=O)c1c[nH]c2ccc(cc12)[N+]([O-])=O Show InChI InChI=1S/C23H23N5O6/c29-23(26-30)5-3-1-2-4-16(19-12-24-21-8-6-14(27(31)32)10-17(19)21)20-13-25-22-9-7-15(28(33)34)11-18(20)22/h6-13,16,24-25,30H,1-5H2,(H,26,29) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
Sigma-Tau Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human HDAC7 by fluroimetry |
Bioorg Med Chem Lett 19: 2840-3 (2009)
Checked by Author Article DOI: 10.1016/j.bmcl.2009.03.101 BindingDB Entry DOI: 10.7270/Q2PN95PT |
More data for this Ligand-Target Pair | |
Histone deacetylase 8
(Homo sapiens (Human)) | BDBM50297446
(CHEMBL561604 | N-hydroxy-7,7-bis(5-nitro-1H-indol-...)Show SMILES ONC(=O)CCCCCC(c1c[nH]c2ccc(cc12)[N+]([O-])=O)c1c[nH]c2ccc(cc12)[N+]([O-])=O Show InChI InChI=1S/C23H23N5O6/c29-23(26-30)5-3-1-2-4-16(19-12-24-21-8-6-14(27(31)32)10-17(19)21)20-13-25-22-9-7-15(28(33)34)11-18(20)22/h6-13,16,24-25,30H,1-5H2,(H,26,29) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Sigma-Tau Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human HDAC8 by fluroimetry |
Bioorg Med Chem Lett 19: 2840-3 (2009)
Checked by Author Article DOI: 10.1016/j.bmcl.2009.03.101 BindingDB Entry DOI: 10.7270/Q2PN95PT |
More data for this Ligand-Target Pair | |
Histone deacetylase 9
(Homo sapiens (Human)) | BDBM50297446
(CHEMBL561604 | N-hydroxy-7,7-bis(5-nitro-1H-indol-...)Show SMILES ONC(=O)CCCCCC(c1c[nH]c2ccc(cc12)[N+]([O-])=O)c1c[nH]c2ccc(cc12)[N+]([O-])=O Show InChI InChI=1S/C23H23N5O6/c29-23(26-30)5-3-1-2-4-16(19-12-24-21-8-6-14(27(31)32)10-17(19)21)20-13-25-22-9-7-15(28(33)34)11-18(20)22/h6-13,16,24-25,30H,1-5H2,(H,26,29) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
Sigma-Tau Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human HDAC9 by fluroimetry |
Bioorg Med Chem Lett 19: 2840-3 (2009)
Checked by Author Article DOI: 10.1016/j.bmcl.2009.03.101 BindingDB Entry DOI: 10.7270/Q2PN95PT |
More data for this Ligand-Target Pair | |
Histone deacetylase 5
(Homo sapiens (Human)) | BDBM50297446
(CHEMBL561604 | N-hydroxy-7,7-bis(5-nitro-1H-indol-...)Show SMILES ONC(=O)CCCCCC(c1c[nH]c2ccc(cc12)[N+]([O-])=O)c1c[nH]c2ccc(cc12)[N+]([O-])=O Show InChI InChI=1S/C23H23N5O6/c29-23(26-30)5-3-1-2-4-16(19-12-24-21-8-6-14(27(31)32)10-17(19)21)20-13-25-22-9-7-15(28(33)34)11-18(20)22/h6-13,16,24-25,30H,1-5H2,(H,26,29) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Sigma-Tau Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human HDAC5 by fluroimetry |
Bioorg Med Chem Lett 19: 2840-3 (2009)
Checked by Author Article DOI: 10.1016/j.bmcl.2009.03.101 BindingDB Entry DOI: 10.7270/Q2PN95PT |
More data for this Ligand-Target Pair | |