BDBM50297563 CHEMBL550813::N''-[2-(1,3-benzothiazol-2-ylthio)-6-methoxy-2,3-dihydro-1H-inden-1-ylidene]carbonohydrazonic diamide hydrochloride

SMILES: [#6]-[#8]-c1ccc2-[#6]-[#6](-[#16]-c3nc4ccccc4s3)-[#6](=[#7]\[#7]=[#6](\[#7])-[#7])-c2c1

InChI Key: InChIKey=RVAQAVSWXAHTBR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50297563   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/hydrogen exchanger 1 (Rattus norvegicus)	BDBM50297563 (CHEMBL550813 | N''-[2-(1,3-benzothiazol-2-ylthio)-...) Show SMILES [#6]-[#8]-c1ccc2-[#6]-[#6](-[#16]-c3nc4ccccc4s3)-[#6](=[#7]\[#7]=[#6](\[#7])-[#7])-c2c1 |w:19.21| Show InChI InChI=1S/C18H17N5OS2/c1-24-11-7-6-10-8-15(16(12(10)9-11)22-23-17(19)20)26-18-21-13-4-2-3-5-14(13)25-18/h2-7,9,15H,8H2,1H3,(H4,19,20,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assay				Eur J Med Chem 44: 3771-6 (2009) Article DOI: 10.1016/j.ejmech.2009.04.036 BindingDB Entry DOI: 10.7270/Q2474BS7
					More data for this Ligand-Target Pair