BDBM50297580 CHEMBL560884::N''-[2-(1,3-benzothiazol-2-ylthio)-5-chloro-2,3-dihydro-1H-inden-1-ylidene]carbonohydrazonic diamide hydrochloride

SMILES: [#7]\[#6](-[#7])=[#7]\[#7]=[#6]-1-[#6](-[#6]-c2cc(Cl)ccc-12)-[#16]-c1nc2ccccc2s1

InChI Key: InChIKey=XFXVEYMMUKMXJN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50297580   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/hydrogen exchanger 1 (Rattus norvegicus)	BDBM50297580 (CHEMBL560884 | N''-[2-(1,3-benzothiazol-2-ylthio)-...) Show SMILES [#7]\[#6](-[#7])=[#7]\[#7]=[#6]-1-[#6](-[#6]-c2cc(Cl)ccc-12)-[#16]-c1nc2ccccc2s1 |w:4.3| Show InChI InChI=1S/C17H14ClN5S2/c18-10-5-6-11-9(7-10)8-14(15(11)22-23-16(19)20)25-17-21-12-3-1-2-4-13(12)24-17/h1-7,14H,8H2,(H4,19,20,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.34	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assay				Eur J Med Chem 44: 3771-6 (2009) Article DOI: 10.1016/j.ejmech.2009.04.036 BindingDB Entry DOI: 10.7270/Q2474BS7
					More data for this Ligand-Target Pair