BDBM50297759 (R)-3-(3-(4-acetylpiperazine-1-carbonyl)-2-hydroxyphenylamino)-4-(1-phenylpropylamino)cyclobut-3-ene-1,2-dione::CHEMBL562670

SMILES: CC[C@@H](Nc1c(Nc2cccc(C(=O)N3CCN(CC3)C(C)=O)c2O)c(=O)c1=O)c1ccccc1

InChI Key: InChIKey=HLMHMNGOPKKOID-LJQANCHMSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50297759   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50297759 ((R)-3-(3-(4-acetylpiperazine-1-carbonyl)-2-hydroxy...) Show SMILES CC[C@@H](Nc1c(Nc2cccc(C(=O)N3CCN(CC3)C(C)=O)c2O)c(=O)c1=O)c1ccccc1 |r| Show InChI InChI=1S/C26H28N4O5/c1-3-19(17-8-5-4-6-9-17)27-21-22(25(34)24(21)33)28-20-11-7-10-18(23(20)32)26(35)30-14-12-29(13-15-30)16(2)31/h4-11,19,27-28,32H,3,12-15H2,1-2H3/t19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of human [125I]IL-8 from human CXCR2				Bioorg Med Chem Lett 19: 4446-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.049 BindingDB Entry DOI: 10.7270/Q2H1323X
					More data for this Ligand-Target Pair