BDBM50297768 1-(2-(5-(3-fluorophenoxy)-2-(pyridin-2-yl)-1H-benzo[d]imidazol-6-yl)pyrrolidin-1-yl)ethanone::CHEMBL561283

SMILES: CC(=O)N1CCCC1c1cc2nc([nH]c2cc1Oc1cccc(F)c1)-c1ccccn1

InChI Key: InChIKey=JNWABOCNQRJLAV-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50297768   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucokinase/Glucokinase regulatory protein (Homo sapiens (Human))	BDBM50297768 (1-(2-(5-(3-fluorophenoxy)-2-(pyridin-2-yl)-1H-benz...) Show SMILES CC(=O)N1CCCC1c1cc2nc([nH]c2cc1Oc1cccc(F)c1)-c1ccccn1 Show InChI InChI=1S/C24H21FN4O2/c1-15(30)29-11-5-9-22(29)18-13-20-21(28-24(27-20)19-8-2-3-10-26-19)14-23(18)31-17-7-4-6-16(25)12-17/h2-4,6-8,10,12-14,22H,5,9,11H2,1H3,(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	930	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop...				Bioorg Med Chem Lett 19: 4450-4 (2009) Article DOI: 10.1016/j.bmcl.2009.05.038 BindingDB Entry DOI: 10.7270/Q27H1JNG
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