BDBM50297898 CHEMBL558025::N-(2-(3-methylphenylsulfonamido)ethyl)-4-phenylpiperidine-1-carboximidamide

SMILES: Cc1cccc(c1)S(=O)(=O)NCCN=C(N)N1CCC(CC1)c1ccccc1

InChI Key: InChIKey=GICQKQBMZRXJLR-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50297898   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50297898 (CHEMBL558025 | N-(2-(3-methylphenylsulfonamido)eth...) Show SMILES Cc1cccc(c1)S(=O)(=O)NCCN=C(N)N1CCC(CC1)c1ccccc1 |w:13.13| Show InChI InChI=1S/C21H28N4O2S/c1-17-6-5-9-20(16-17)28(26,27)24-13-12-23-21(22)25-14-10-19(11-15-25)18-7-3-2-4-8-18/h2-9,16,19,24H,10-15H2,1H3,(H2,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to 5HT2A receptor in rat cortex				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50297898 (CHEMBL558025 | N-(2-(3-methylphenylsulfonamido)eth...) Show SMILES Cc1cccc(c1)S(=O)(=O)NCCN=C(N)N1CCC(CC1)c1ccccc1 |w:13.13| Show InChI InChI=1S/C21H28N4O2S/c1-17-6-5-9-20(16-17)28(26,27)24-13-12-23-21(22)25-14-10-19(11-15-25)18-7-3-2-4-8-18/h2-9,16,19,24H,10-15H2,1H3,(H2,22,23)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	161	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to human cloned 5HT7 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50297898 (CHEMBL558025 | N-(2-(3-methylphenylsulfonamido)eth...) Show SMILES Cc1cccc(c1)S(=O)(=O)NCCN=C(N)N1CCC(CC1)c1ccccc1 |w:13.13| Show InChI InChI=1S/C21H28N4O2S/c1-17-6-5-9-20(16-17)28(26,27)24-13-12-23-21(22)25-14-10-19(11-15-25)18-7-3-2-4-8-18/h2-9,16,19,24H,10-15H2,1H3,(H2,22,23)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.56E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to 5HT1A receptor in rat hippocampus				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair