BDBM50297986 5-(pyrazolo[1,5-a]pyridin-3-yl)-3-(2-(trifluoromethyl)benzyloxy)thiophene-2-carboxamide::CHEMBL559891

SMILES: NC(=O)c1sc(cc1OCc1ccccc1C(F)(F)F)-c1cnn2ccccc12

InChI Key: InChIKey=PAUHHPAGKWCLHG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50297986   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM50297986 (5-(pyrazolo[1,5-a]pyridin-3-yl)-3-(2-(trifluoromet...) Show SMILES NC(=O)c1sc(cc1OCc1ccccc1C(F)(F)F)-c1cnn2ccccc12 Show InChI InChI=1S/C20H14F3N3O2S/c21-20(22,23)14-6-2-1-5-12(14)11-28-16-9-17(29-18(16)19(24)27)13-10-25-26-8-4-3-7-15(13)26/h1-10H,11H2,(H2,24,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Inhibition of PLK1				Bioorg Med Chem Lett 19: 4673-8 (2009) Article DOI: 10.1016/j.bmcl.2009.06.084 BindingDB Entry DOI: 10.7270/Q22R3RQG
					More data for this Ligand-Target Pair