BDBM50298001 (+/-)-5-(2-fluoropyridin-3-yl)-4,5,6,7-tetrahydro-1H-indazole-3-carboxylic acid::5-(2-fluoropyridin-3-yl)-4,5,6,7-tetrahydro-1H-indazole-3-carboxylic acid, hydrobromide::5-(2-fluoropyridin-3-yl)-4,5,6,7-tetrahydro-1H-indazole-3-carboxylic acid, hydrochloride::CHEMBL1237147::CHEMBL539398

SMILES: OC(=O)c1n[nH]c2CCC(Cc12)c1cccnc1F

InChI Key: InChIKey=JQOSYJBFVAFNNY-UHFFFAOYSA-N

Data: 4 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50298001   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50298001 ((+/-)-5-(2-fluoropyridin-3-yl)-4,5,6,7-tetrahydro-...) Show SMILES OC(=O)c1n[nH]c2CCC(Cc12)c1cccnc1F Show InChI InChI=1S/C13H12FN3O2/c14-12-8(2-1-5-15-12)7-3-4-10-9(6-7)11(13(18)19)17-16-10/h1-2,5,7H,3-4,6H2,(H,16,17)(H,18,19)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]niacin from human niacin receptor expressed in CKO-K1 cells in absence of 5% human serum				Bioorg Med Chem Lett 19: 4768-72 (2009) Article DOI: 10.1016/j.bmcl.2009.06.054 BindingDB Entry DOI: 10.7270/Q2M909M3
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50298001 ((+/-)-5-(2-fluoropyridin-3-yl)-4,5,6,7-tetrahydro-...) Show SMILES OC(=O)c1n[nH]c2CCC(Cc12)c1cccnc1F Show InChI InChI=1S/C13H12FN3O2/c14-12-8(2-1-5-15-12)7-3-4-10-9(6-7)11(13(18)19)17-16-10/h1-2,5,7H,3-4,6H2,(H,16,17)(H,18,19)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	850	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]niacin from human niacin receptor expressed in CKO-K1 cells in presence of 5% human serum				Bioorg Med Chem Lett 19: 4768-72 (2009) Article DOI: 10.1016/j.bmcl.2009.06.054 BindingDB Entry DOI: 10.7270/Q2M909M3
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50298001 ((+/-)-5-(2-fluoropyridin-3-yl)-4,5,6,7-tetrahydro-...) Show SMILES OC(=O)c1n[nH]c2CCC(Cc12)c1cccnc1F Show InChI InChI=1S/C13H12FN3O2/c14-12-8(2-1-5-15-12)7-3-4-10-9(6-7)11(13(18)19)17-16-10/h1-2,5,7H,3-4,6H2,(H,16,17)(H,18,19)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at human niacin receptor expressed in CKO-K1 cells by [35S]GTPgammaS binding assay				Bioorg Med Chem Lett 19: 4768-72 (2009) Article DOI: 10.1016/j.bmcl.2009.06.054 BindingDB Entry DOI: 10.7270/Q2M909M3
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50298001 ((+/-)-5-(2-fluoropyridin-3-yl)-4,5,6,7-tetrahydro-...) Show SMILES OC(=O)c1n[nH]c2CCC(Cc12)c1cccnc1F Show InChI InChI=1S/C13H12FN3O2/c14-12-8(2-1-5-15-12)7-3-4-10-9(6-7)11(13(18)19)17-16-10/h1-2,5,7H,3-4,6H2,(H,16,17)(H,18,19)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]niacin from human niacin receptor expressed in CKO-K1 cells in absence of 5% human serum				Bioorg Med Chem Lett 19: 4768-72 (2009) Article DOI: 10.1016/j.bmcl.2009.06.054 BindingDB Entry DOI: 10.7270/Q2M909M3
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50298001 ((+/-)-5-(2-fluoropyridin-3-yl)-4,5,6,7-tetrahydro-...) Show SMILES OC(=O)c1n[nH]c2CCC(Cc12)c1cccnc1F Show InChI InChI=1S/C13H12FN3O2/c14-12-8(2-1-5-15-12)7-3-4-10-9(6-7)11(13(18)19)17-16-10/h1-2,5,7H,3-4,6H2,(H,16,17)(H,18,19)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]niacin from human niacin receptor expressed in CKO-K1 cells in presence of 5% human serum				Bioorg Med Chem Lett 19: 4768-72 (2009) Article DOI: 10.1016/j.bmcl.2009.06.054 BindingDB Entry DOI: 10.7270/Q2M909M3
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50298001 ((+/-)-5-(2-fluoropyridin-3-yl)-4,5,6,7-tetrahydro-...) Show SMILES OC(=O)c1n[nH]c2CCC(Cc12)c1cccnc1F Show InChI InChI=1S/C13H12FN3O2/c14-12-8(2-1-5-15-12)7-3-4-10-9(6-7)11(13(18)19)17-16-10/h1-2,5,7H,3-4,6H2,(H,16,17)(H,18,19)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at human niacin receptor expressed in CKO-K1 cells by [35S]GTPgammaS binding assay				Bioorg Med Chem Lett 19: 4768-72 (2009) Article DOI: 10.1016/j.bmcl.2009.06.054 BindingDB Entry DOI: 10.7270/Q2M909M3
					More data for this Ligand-Target Pair