BDBM50298041 (S)-4-(benzyl(1-methylpyrrolidin-3-yl)amino)-2-chlorobenzonitrile::CHEMBL550270

SMILES: CN1CC[C@@H](C1)N(Cc1ccccc1)c1ccc(C#N)c(Cl)c1

InChI Key: InChIKey=CMNWDIVNTOBUQU-SFHVURJKSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50298041   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50298041 ((S)-4-(benzyl(1-methylpyrrolidin-3-yl)amino)-2-chl...) Show SMILES CN1CC[C@@H](C1)N(Cc1ccccc1)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C19H20ClN3/c1-22-10-9-18(14-22)23(13-15-5-3-2-4-6-15)17-8-7-16(12-21)19(20)11-17/h2-8,11,18H,9-10,13-14H2,1H3/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50298041 ((S)-4-(benzyl(1-methylpyrrolidin-3-yl)amino)-2-chl...) Show SMILES CN1CC[C@@H](C1)N(Cc1ccccc1)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C19H20ClN3/c1-22-10-9-18(14-22)23(13-15-5-3-2-4-6-15)17-8-7-16(12-21)19(20)11-17/h2-8,11,18H,9-10,13-14H2,1H3/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to PR by fluorescence polarization based competition binding assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair