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SMILES: CN1CC[C@@H](C1)N(Cc1cccc(Cl)c1)c1ccc(C#N)c(Cl)c1

InChI Key: InChIKey=MWKNUGHHPUTDRR-SFHVURJKSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50298044   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50298044 ((S)-2-chloro-4-((3-chlorobenzyl)(1-methylpyrrolidi...) Show SMILES CN1CC[C@@H](C1)N(Cc1cccc(Cl)c1)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C19H19Cl2N3/c1-23-8-7-18(13-23)24(12-14-3-2-4-16(20)9-14)17-6-5-15(11-22)19(21)10-17/h2-6,9-10,18H,7-8,12-13H2,1H3/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50298044 ((S)-2-chloro-4-((3-chlorobenzyl)(1-methylpyrrolidi...) Show SMILES CN1CC[C@@H](C1)N(Cc1cccc(Cl)c1)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C19H19Cl2N3/c1-23-8-7-18(13-23)24(12-14-3-2-4-16(20)9-14)17-6-5-15(11-22)19(21)10-17/h2-6,9-10,18H,7-8,12-13H2,1H3/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to PR by fluorescence polarization based competition binding assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair