BDBM50298217 4-(((3S)-1-sec-butyl-5-oxopyrrolidin-3-yl)(2-methylbenzyl)amino)-2-chlorobenzonitrile::CHEMBL552492

SMILES: CCC(C)N1C[C@H](CC1=O)N(Cc1ccccc1C)c1ccc(C#N)c(Cl)c1

InChI Key: InChIKey=MYDCMDSRMKJEGU-LFABVHOISA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50298217   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50298217 (4-(((3S)-1-sec-butyl-5-oxopyrrolidin-3-yl)(2-methy...) Show SMILES CCC(C)N1C[C@H](CC1=O)N(Cc1ccccc1C)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C23H26ClN3O/c1-4-17(3)26-15-21(12-23(26)28)27(14-19-8-6-5-7-16(19)2)20-10-9-18(13-25)22(24)11-20/h5-11,17,21H,4,12,14-15H2,1-3H3/t17?,21-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	750	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity				Bioorg Med Chem Lett 19: 4664-8 (2009) Article DOI: 10.1016/j.bmcl.2009.06.081 BindingDB Entry DOI: 10.7270/Q25H7G9T
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50298217 (4-(((3S)-1-sec-butyl-5-oxopyrrolidin-3-yl)(2-methy...) Show SMILES CCC(C)N1C[C@H](CC1=O)N(Cc1ccccc1C)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C23H26ClN3O/c1-4-17(3)26-15-21(12-23(26)28)27(14-19-8-6-5-7-16(19)2)20-10-9-18(13-25)22(24)11-20/h5-11,17,21H,4,12,14-15H2,1-3H3/t17?,21-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	125	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to progesterone receptor				Bioorg Med Chem Lett 19: 4664-8 (2009) Article DOI: 10.1016/j.bmcl.2009.06.081 BindingDB Entry DOI: 10.7270/Q25H7G9T
					More data for this Ligand-Target Pair