BDBM50298372 2,2'-[4,5-Acridindiylbis(methyleneimino)]bis[N-methyl-N-(3-oxopropyl)pyrrolidinium]diiodide::CHEMBL566078

SMILES: C[N+]1(CCC(=O)NCc2cccc3cc4cccc(CNC(=O)CC[N+]5(C)CCCC5)c4nc23)CCCC1

InChI Key: InChIKey=SROHNEWTGIPHCS-UHFFFAOYSA-P

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50298372   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50298372 (2,2'-[4,5-Acridindiylbis(methyleneimino)]bis[N-met...) Show SMILES C[N+]1(CCC(=O)NCc2cccc3cc4cccc(CNC(=O)CC[N+]5(C)CCCC5)c4nc23)CCCC1 Show InChI InChI=1S/C31H41N5O2/c1-35(15-3-4-16-35)19-13-28(37)32-22-26-11-7-9-24-21-25-10-8-12-27(31(25)34-30(24)26)23-33-29(38)14-20-36(2)17-5-6-18-36/h7-12,21H,3-6,13-20,22-23H2,1-2H3/p+2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Reims-Champagne-Ardenne Curated by ChEMBL					Assay Description Inhibition of human telomerase in A549 cells by TRAP assay				Eur J Med Chem 44: 3880-8 (2009) Article DOI: 10.1016/j.ejmech.2009.04.021 BindingDB Entry DOI: 10.7270/Q2W37WDH
					More data for this Ligand-Target Pair