BDBM50298663 (R)-Methyl 2-(3-(cyclohexylcarbamoyloxy)phenyl)-4,5-dihydrooxazole-4-carboxylate::CHEMBL574077

SMILES: COC(=O)[C@H]1COC(=N1)c1cccc(OC(=O)NC2CCCCC2)c1

InChI Key: InChIKey=HAMTZHORKYWWPS-OAHLLOKOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50298663   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat))	BDBM50298663 ((R)-Methyl 2-(3-(cyclohexylcarbamoyloxy)phenyl)-4,...) Show SMILES COC(=O)[C@H]1COC(=N1)c1cccc(OC(=O)NC2CCCCC2)c1 |r,c:7| Show InChI InChI=1S/C18H22N2O5/c1-23-17(21)15-11-24-16(20-15)12-6-5-9-14(10-12)25-18(22)19-13-7-3-2-4-8-13/h5-6,9-10,13,15H,2-4,7-8,11H2,1H3,(H,19,22)/t15-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Helsinki University of Technology Curated by ChEMBL					Assay Description Inhibition of FAAH in Wistar rat brain assessed as by liquid scintillation counting				Eur J Med Chem 44: 4179-91 (2009) Article DOI: 10.1016/j.ejmech.2009.05.012 BindingDB Entry DOI: 10.7270/Q2FT8M3R
					More data for this Ligand-Target Pair