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SMILES: Fc1ccc(NC(=O)c2ccc3c(Nc4ccccc4NC3=O)c2)cc1

InChI Key: InChIKey=DSRGVBKRHCMKHJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50299239   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Beta-secretase 1


(Homo sapiens (Human))		BDBM50299239
PNG
(CHEMBL572940 | N-(4-Fluorophenyl)-11-oxo-10,11-dih...)
Show SMILES Fc1ccc(NC(=O)c2ccc3c(Nc4ccccc4NC3=O)c2)cc1
Show InChI InChI=1S/C20H14FN3O2/c21-13-6-8-14(9-7-13)22-19(25)12-5-10-15-18(11-12)23-16-3-1-2-4-17(16)24-20(15)26/h1-11,23H,(H,22,25)(H,24,26)
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KEGG

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Similars
Article
PubMed
 211n/an/an/an/an/an/an/an/a



University of Sharjah

Curated by ChEMBL


Assay Description
Inhibition of human recombinant BACE1 by FRET assay

J Med Chem 52: 6484-8 (2009)


Article DOI: 10.1021/jm9008482
BindingDB Entry DOI: 10.7270/Q2765FC2
More data for this
Ligand-Target Pair