BDBM50299248 1,10-Dihydropyrrolo[2,3-a]carbazole-3-carboxamide::CHEMBL573176::US8481586, 5

SMILES: NC(=O)c1c[nH]c2c1ccc1c3ccccc3[nH]c21

InChI Key: InChIKey=MXZKCOUOYWSEKW-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50299248   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50299248 (1,10-Dihydropyrrolo[2,3-a]carbazole-3-carboxamide ...) Show SMILES NC(=O)c1c[nH]c2c1ccc1c3ccccc3[nH]c21 Show InChI InChI=1S/C15H11N3O/c16-15(19)11-7-17-13-10(11)6-5-9-8-3-1-2-4-12(8)18-14(9)13/h1-7,17-18H,(H2,16,19)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	US Patent	n/a	n/a	780	n/a	n/a	n/a	n/a	n/a	n/a
Centre National de la Recherche Scientifique; Universite Blaise Pascal-Clermont-Ferrand II US Patent					Assay Description Inhibition assay using PIM-1, PIM-2 and PIM-3.				US Patent US8481586 (2013) BindingDB Entry DOI: 10.7270/Q2ZC81GT
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50299248 (1,10-Dihydropyrrolo[2,3-a]carbazole-3-carboxamide ...) Show SMILES NC(=O)c1c[nH]c2c1ccc1c3ccccc3[nH]c21 Show InChI InChI=1S/C15H11N3O/c16-15(19)11-7-17-13-10(11)6-5-9-8-3-1-2-4-12(8)18-14(9)13/h1-7,17-18H,(H2,16,19)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	780	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of Pim-1				J Med Chem 52: 6369-81 (2009) Article DOI: 10.1021/jm901018f BindingDB Entry DOI: 10.7270/Q23F4PPS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50299248 (1,10-Dihydropyrrolo[2,3-a]carbazole-3-carboxamide ...) Show SMILES NC(=O)c1c[nH]c2c1ccc1c3ccccc3[nH]c21 Show InChI InChI=1S/C15H11N3O/c16-15(19)11-7-17-13-10(11)6-5-9-8-3-1-2-4-12(8)18-14(9)13/h1-7,17-18H,(H2,16,19)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of Pim-3				J Med Chem 52: 6369-81 (2009) Article DOI: 10.1021/jm901018f BindingDB Entry DOI: 10.7270/Q23F4PPS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50299248 (1,10-Dihydropyrrolo[2,3-a]carbazole-3-carboxamide ...) Show SMILES NC(=O)c1c[nH]c2c1ccc1c3ccccc3[nH]c21 Show InChI InChI=1S/C15H11N3O/c16-15(19)11-7-17-13-10(11)6-5-9-8-3-1-2-4-12(8)18-14(9)13/h1-7,17-18H,(H2,16,19)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	US Patent	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Centre National de la Recherche Scientifique; Universite Blaise Pascal-Clermont-Ferrand II US Patent					Assay Description Inhibition assay using PIM-1, PIM-2 and PIM-3.				US Patent US8481586 (2013) BindingDB Entry DOI: 10.7270/Q2ZC81GT
					More data for this Ligand-Target Pair