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BDBM50299290 1'-Benzhydryl-3-(3-fluoropropyl)-3H-spiro[[2]benzofuran-1,4'-piperidine]::CHEMBL575127

SMILES: FCCCC1OC2(CCN(CC2)C(c2ccccc2)c2ccccc2)c2ccccc12

InChI Key: InChIKey=ZGGFCMHHXYXYPA-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50299290   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50299290
PNG
(1'-Benzhydryl-3-(3-fluoropropyl)-3H-spiro[[2]benzo...)
Show SMILES FCCCC1OC2(CCN(CC2)C(c2ccccc2)c2ccccc2)c2ccccc12
Show InChI InChI=1S/C28H30FNO/c29-19-9-16-26-24-14-7-8-15-25(24)28(31-26)17-20-30(21-18-28)27(22-10-3-1-4-11-22)23-12-5-2-6-13-23/h1-8,10-15,26-27H,9,16-21H2
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Similars
Article
PubMed
 1.11E+3n/an/an/an/an/an/an/an/a



Institut f£r Pharmazeutische und Medizinische Chemie der Westf£lischen Wilhelms-Universit£t M£nster

Curated by ChEMBL


Assay Description
Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membrane after 180 mins by scintillation counting

J Med Chem 52: 6062-72 (2009)


Article DOI: 10.1021/jm900909e
BindingDB Entry DOI: 10.7270/Q2KH0ND9
More data for this
Ligand-Target Pair