BDBM50299423 2-{7-[(3-Chlorobenzyl)oxy]-2-oxo-2H-chromen-4-yl}-N,N-dimethylacetamide::CHEMBL577616

SMILES: CN(C)C(=O)Cc1cc(=O)oc2cc(OCc3cccc(Cl)c3)ccc12

InChI Key: InChIKey=OUHPLYFBOFCGTB-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50299423   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat))	BDBM50299423 (2-{7-[(3-Chlorobenzyl)oxy]-2-oxo-2H-chromen-4-yl}-...) Show SMILES CN(C)C(=O)Cc1cc(=O)oc2cc(OCc3cccc(Cl)c3)ccc12 Show InChI InChI=1S/C20H18ClNO4/c1-22(2)19(23)9-14-10-20(24)26-18-11-16(6-7-17(14)18)25-12-13-4-3-5-15(21)8-13/h3-8,10-11H,9,12H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari"Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of Sprague-Dawley rat MAO-B in brain mitochondrial homogenate assessed as 4-hydroxyquinoline by spectrophotometric method				Eur J Med Chem 89: 98-105 (2014) Article DOI: 10.1016/j.ejmech.2014.10.029 BindingDB Entry DOI: 10.7270/Q2FX7C3H
					More data for this Ligand-Target Pair
Monoamine oxidase (Rattus norvegicus (rat))	BDBM50299423 (2-{7-[(3-Chlorobenzyl)oxy]-2-oxo-2H-chromen-4-yl}-...) Show SMILES CN(C)C(=O)Cc1cc(=O)oc2cc(OCc3cccc(Cl)c3)ccc12 Show InChI InChI=1S/C20H18ClNO4/c1-22(2)19(23)9-14-10-20(24)26-18-11-16(6-7-17(14)18)25-12-13-4-3-5-15(21)8-13/h3-8,10-11H,9,12H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of Sprague-Dawley rat MAO-B using Kynuramine as substrate assessed as formation of 4-hydroxyquinoline preincubated for 5 mins prior to sub...				Eur J Med Chem 70: 723-39 (2013) Article DOI: 10.1016/j.ejmech.2013.09.034 BindingDB Entry DOI: 10.7270/Q2WM1HCD
					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat))	BDBM50299423 (2-{7-[(3-Chlorobenzyl)oxy]-2-oxo-2H-chromen-4-yl}-...) Show SMILES CN(C)C(=O)Cc1cc(=O)oc2cc(OCc3cccc(Cl)c3)ccc12 Show InChI InChI=1S/C20H18ClNO4/c1-22(2)19(23)9-14-10-20(24)26-18-11-16(6-7-17(14)18)25-12-13-4-3-5-15(21)8-13/h3-8,10-11H,9,12H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Bari Curated by ChEMBL					Assay Description Inhibition of MAO-B from Wistar rat brain by radioenzymatic assay				J Med Chem 52: 6685-706 (2009) Article DOI: 10.1021/jm9010127 BindingDB Entry DOI: 10.7270/Q2DR2VJ6
					More data for this Ligand-Target Pair
Monoamine oxidase (Rattus norvegicus (rat))	BDBM50299423 (2-{7-[(3-Chlorobenzyl)oxy]-2-oxo-2H-chromen-4-yl}-...) Show SMILES CN(C)C(=O)Cc1cc(=O)oc2cc(OCc3cccc(Cl)c3)ccc12 Show InChI InChI=1S/C20H18ClNO4/c1-22(2)19(23)9-14-10-20(24)26-18-11-16(6-7-17(14)18)25-12-13-4-3-5-15(21)8-13/h3-8,10-11H,9,12H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Bari Curated by ChEMBL					Assay Description Inhibition of MAO-A from Wistar rat brain by radioenzymatic assay				J Med Chem 52: 6685-706 (2009) Article DOI: 10.1021/jm9010127 BindingDB Entry DOI: 10.7270/Q2DR2VJ6
					More data for this Ligand-Target Pair