BDBM50299444 1-{7-[(3-Chlorobenzyl)oxy]-2-oxo-2H-chromen-4-yl}prolinamide::CHEMBL575732

SMILES: NC(=O)[C@@H]1CCCN1c1cc(=O)oc2cc(OCc3cccc(Cl)c3)ccc12

InChI Key: InChIKey=QJWPAVVFJOUUOW-KRWDZBQOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50299444   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat))	BDBM50299444 (1-{7-[(3-Chlorobenzyl)oxy]-2-oxo-2H-chromen-4-yl}p...) Show SMILES NC(=O)[C@@H]1CCCN1c1cc(=O)oc2cc(OCc3cccc(Cl)c3)ccc12 |r| Show InChI InChI=1S/C21H19ClN2O4/c22-14-4-1-3-13(9-14)12-27-15-6-7-16-18(11-20(25)28-19(16)10-15)24-8-2-5-17(24)21(23)26/h1,3-4,6-7,9-11,17H,2,5,8,12H2,(H2,23,26)/t17-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Bari Curated by ChEMBL					Assay Description Inhibition of MAO-B from Wistar rat brain by radioenzymatic assay				J Med Chem 52: 6685-706 (2009) Article DOI: 10.1021/jm9010127 BindingDB Entry DOI: 10.7270/Q2DR2VJ6
					More data for this Ligand-Target Pair