BDBM50299458 2-{7-[(3-Chlorobenzyl)oxy]-2-oxo-2H-chromen-4-yl}-N-methylacetamide::CHEMBL575931

SMILES: CNC(=O)Cc1cc(=O)oc2cc(OCc3cccc(Cl)c3)ccc12

InChI Key: InChIKey=SQDHAAAUCSVUIM-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50299458   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat))	BDBM50299458 (2-{7-[(3-Chlorobenzyl)oxy]-2-oxo-2H-chromen-4-yl}-...) Show SMILES CNC(=O)Cc1cc(=O)oc2cc(OCc3cccc(Cl)c3)ccc12 Show InChI InChI=1S/C19H16ClNO4/c1-21-18(22)8-13-9-19(23)25-17-10-15(5-6-16(13)17)24-11-12-3-2-4-14(20)7-12/h2-7,9-10H,8,11H2,1H3,(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari"Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of Sprague-Dawley rat MAO-B in brain mitochondrial homogenate assessed as 4-hydroxyquinoline by spectrophotometric method				Eur J Med Chem 89: 98-105 (2014) Article DOI: 10.1016/j.ejmech.2014.10.029 BindingDB Entry DOI: 10.7270/Q2FX7C3H
					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat))	BDBM50299458 (2-{7-[(3-Chlorobenzyl)oxy]-2-oxo-2H-chromen-4-yl}-...) Show SMILES CNC(=O)Cc1cc(=O)oc2cc(OCc3cccc(Cl)c3)ccc12 Show InChI InChI=1S/C19H16ClNO4/c1-21-18(22)8-13-9-19(23)25-17-10-15(5-6-16(13)17)24-11-12-3-2-4-14(20)7-12/h2-7,9-10H,8,11H2,1H3,(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Bari Curated by ChEMBL					Assay Description Inhibition of MAO-B from Wistar rat brain by radioenzymatic assay				J Med Chem 52: 6685-706 (2009) Article DOI: 10.1021/jm9010127 BindingDB Entry DOI: 10.7270/Q2DR2VJ6
					More data for this Ligand-Target Pair
Monoamine oxidase (Rattus norvegicus (rat))	BDBM50299458 (2-{7-[(3-Chlorobenzyl)oxy]-2-oxo-2H-chromen-4-yl}-...) Show SMILES CNC(=O)Cc1cc(=O)oc2cc(OCc3cccc(Cl)c3)ccc12 Show InChI InChI=1S/C19H16ClNO4/c1-21-18(22)8-13-9-19(23)25-17-10-15(5-6-16(13)17)24-11-12-3-2-4-14(20)7-12/h2-7,9-10H,8,11H2,1H3,(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of Sprague-Dawley rat MAO-B using Kynuramine as substrate assessed as formation of 4-hydroxyquinoline preincubated for 5 mins prior to sub...				Eur J Med Chem 70: 723-39 (2013) Article DOI: 10.1016/j.ejmech.2013.09.034 BindingDB Entry DOI: 10.7270/Q2WM1HCD
					More data for this Ligand-Target Pair
Monoamine oxidase (Rattus norvegicus (rat))	BDBM50299458 (2-{7-[(3-Chlorobenzyl)oxy]-2-oxo-2H-chromen-4-yl}-...) Show SMILES CNC(=O)Cc1cc(=O)oc2cc(OCc3cccc(Cl)c3)ccc12 Show InChI InChI=1S/C19H16ClNO4/c1-21-18(22)8-13-9-19(23)25-17-10-15(5-6-16(13)17)24-11-12-3-2-4-14(20)7-12/h2-7,9-10H,8,11H2,1H3,(H,21,22)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	501	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of Sprague-Dawley rat MAO-A using Kynuramine as substrate assessed as formation of 4-hydroxyquinoline preincubated for 5 mins prior to sub...				Eur J Med Chem 70: 723-39 (2013) Article DOI: 10.1016/j.ejmech.2013.09.034 BindingDB Entry DOI: 10.7270/Q2WM1HCD
					More data for this Ligand-Target Pair
Monoamine oxidase (Rattus norvegicus (rat))	BDBM50299458 (2-{7-[(3-Chlorobenzyl)oxy]-2-oxo-2H-chromen-4-yl}-...) Show SMILES CNC(=O)Cc1cc(=O)oc2cc(OCc3cccc(Cl)c3)ccc12 Show InChI InChI=1S/C19H16ClNO4/c1-21-18(22)8-13-9-19(23)25-17-10-15(5-6-16(13)17)24-11-12-3-2-4-14(20)7-12/h2-7,9-10H,8,11H2,1H3,(H,21,22)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Bari Curated by ChEMBL					Assay Description Inhibition of MAO-A from Wistar rat brain by radioenzymatic assay				J Med Chem 52: 6685-706 (2009) Article DOI: 10.1021/jm9010127 BindingDB Entry DOI: 10.7270/Q2DR2VJ6
					More data for this Ligand-Target Pair