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SMILES: COc1cccc(NC(=O)N2CCN(CC2)c2ncnc3[nH]cc(C)c23)c1

InChI Key: InChIKey=FXQYSASDTKPUOS-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50299596   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
LIM domain kinase 2


(Homo sapiens (Human))		BDBM50299596
PNG
(CHEMBL568706 | N-(3-methoxyphenyl)-4-(5-methyl-7H-...)
Show SMILES COc1cccc(NC(=O)N2CCN(CC2)c2ncnc3[nH]cc(C)c23)c1
Show InChI InChI=1S/C19H22N6O2/c1-13-11-20-17-16(13)18(22-12-21-17)24-6-8-25(9-7-24)19(26)23-14-4-3-5-15(10-14)27-2/h3-5,10-12H,6-9H2,1-2H3,(H,23,26)(H,20,21,22)
PDB
MMDB

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Similars
Article
PubMed
n/an/a 140n/an/an/an/an/an/a



Princ

Curated by ChEMBL


Assay Description
Inhibition of human recombinant LIMK2 expressed in baculovirus-Sf9 system by scintillation counting

J Med Chem 52: 6515-8 (2009)


Article DOI: 10.1021/jm901226j
BindingDB Entry DOI: 10.7270/Q2HH6K4J
More data for this
Ligand-Target Pair