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SMILES: COc1cc2nccc(N(C)c3ccc(NC(=O)N4CCN(C4=O)c4ccccc4)cc3F)c2cc1OC

InChI Key: InChIKey=PIBYAUKKXDSVPW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50299776   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50299776
PNG
(CHEMBL575490 | N-(4-((6,7-dimethoxyquinolin-4-yl)(...)
Show SMILES COc1cc2nccc(N(C)c3ccc(NC(=O)N4CCN(C4=O)c4ccccc4)cc3F)c2cc1OC
Show InChI InChI=1S/C28H26FN5O4/c1-32(23-11-12-30-22-17-26(38-3)25(37-2)16-20(22)23)24-10-9-18(15-21(24)29)31-27(35)34-14-13-33(28(34)36)19-7-5-4-6-8-19/h4-12,15-17H,13-14H2,1-3H3,(H,31,35)
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n/an/a 400n/an/an/an/an/an/a



MethylGene Inc

Curated by ChEMBL


Assay Description
Inhibition of GST-tagged c-Met expressed in Sf9 cells

Bioorg Med Chem Lett 19: 6552-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.040
BindingDB Entry DOI: 10.7270/Q2VM4D6R
More data for this
Ligand-Target Pair