null

SMILES: COc1cc2ncnc(N(C)c3ccc(NC(=O)N4CCN(C4=O)c4ccccc4)cc3F)c2cc1OC

InChI Key: InChIKey=QJDQJXUQXCUXFN-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50299780   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50299780 (CHEMBL574863 | N-(4-((6,7-dimethoxyquinazolin-4-yl...) Show SMILES COc1cc2ncnc(N(C)c3ccc(NC(=O)N4CCN(C4=O)c4ccccc4)cc3F)c2cc1OC Show InChI InChI=1S/C27H25FN6O4/c1-32(25-19-14-23(37-2)24(38-3)15-21(19)29-16-30-25)22-10-9-17(13-20(22)28)31-26(35)34-12-11-33(27(34)36)18-7-5-4-6-8-18/h4-10,13-16H,11-12H2,1-3H3,(H,31,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
MethylGene Inc Curated by ChEMBL					Assay Description Inhibition of GST-tagged c-Met expressed in Sf9 cells				Bioorg Med Chem Lett 19: 6552-6 (2009) Article DOI: 10.1016/j.bmcl.2009.10.040 BindingDB Entry DOI: 10.7270/Q2VM4D6R
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50299780 (CHEMBL574863 | N-(4-((6,7-dimethoxyquinazolin-4-yl...) Show SMILES COc1cc2ncnc(N(C)c3ccc(NC(=O)N4CCN(C4=O)c4ccccc4)cc3F)c2cc1OC Show InChI InChI=1S/C27H25FN6O4/c1-32(25-19-14-23(37-2)24(38-3)15-21(19)29-16-30-25)22-10-9-17(13-20(22)28)31-26(35)34-12-11-33(27(34)36)18-7-5-4-6-8-18/h4-10,13-16H,11-12H2,1-3H3,(H,31,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
MethylGene Inc Curated by ChEMBL					Assay Description Inhibition of TPR-Met assessed as autophosphorylation				Bioorg Med Chem Lett 19: 6552-6 (2009) Article DOI: 10.1016/j.bmcl.2009.10.040 BindingDB Entry DOI: 10.7270/Q2VM4D6R
					More data for this Ligand-Target Pair