BDBM50300309 4-Amino-N-(3-chlorophenyl)-1,2,5-oxadiazole-3-carbohydrazonamide::CHEMBL567441

SMILES: NNC(=Nc1cccc(Cl)c1)c1nonc1N

InChI Key: InChIKey=DRLJJRCCKOMJER-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50300309   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Indoleamine 2,3-dioxygenase (Homo sapiens (Human))	BDBM50300309 (4-Amino-N-(3-chlorophenyl)-1,2,5-oxadiazole-3-carb...) Show SMILES NNC(=Nc1cccc(Cl)c1)c1nonc1N |w:3.3| Show InChI InChI=1S/C9H9ClN6O/c10-5-2-1-3-6(4-5)13-9(14-12)7-8(11)16-17-15-7/h1-4H,12H2,(H2,11,16)(H,13,14)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation Curated by ChEMBL					Assay Description Inhibition of indoleamine 2,3-dioxygenase in IFN-gamma-stimulated human HeLa cells assessed as kynurenine formation by spectrophotometry				J Med Chem 52: 7364-7 (2009) Article DOI: 10.1021/jm900518f BindingDB Entry DOI: 10.7270/Q29P32KW
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase (Homo sapiens (Human))	BDBM50300309 (4-Amino-N-(3-chlorophenyl)-1,2,5-oxadiazole-3-carb...) Show SMILES NNC(=Nc1cccc(Cl)c1)c1nonc1N |w:3.3| Show InChI InChI=1S/C9H9ClN6O/c10-5-2-1-3-6(4-5)13-9(14-12)7-8(11)16-17-15-7/h1-4H,12H2,(H2,11,16)(H,13,14)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation Curated by ChEMBL					Assay Description Inhibition of N-terminal his-tagged human indoleamine 2,3-dioxygenase expressed in Escherichia coli assessed as N'-formylkynurenine formation by spec...				J Med Chem 52: 7364-7 (2009) Article DOI: 10.1021/jm900518f BindingDB Entry DOI: 10.7270/Q29P32KW
					More data for this Ligand-Target Pair