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SMILES: CNC1CCN(CC1)c1ccc(Nc2ncc(Cl)c(Nc3ccccc3S(=O)(=O)C(C)C)n2)c(OC)c1

InChI Key: InChIKey=QMPDIVCUYSILPX-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50300397   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase ZAP-70


(Homo sapiens (Human))		BDBM50300397
PNG
(5-chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(2-me...)
Show SMILES CNC1CCN(CC1)c1ccc(Nc2ncc(Cl)c(Nc3ccccc3S(=O)(=O)C(C)C)n2)c(OC)c1
Show InChI InChI=1S/C26H33ClN6O3S/c1-17(2)37(34,35)24-8-6-5-7-22(24)30-25-20(27)16-29-26(32-25)31-21-10-9-19(15-23(21)36-4)33-13-11-18(28-3)12-14-33/h5-10,15-18,28H,11-14H2,1-4H3,(H2,29,30,31,32)
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PubMed
n/an/a 2.00E+3n/an/an/an/an/an/a



GVK Biosciences Pvt. Ltd.

Curated by ChEMBL


Assay Description
Inhibition of human GST-fused ZAP-70 expressed in Sf9 cells

Eur J Med Chem 44: 4793-800 (2009)


Article DOI: 10.1016/j.ejmech.2009.07.018
BindingDB Entry DOI: 10.7270/Q25X290Z
More data for this
Ligand-Target Pair