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SMILES: CCn1sc(Cl)c(C)c1=O

InChI Key: InChIKey=PWQFDYMZDPXLEG-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50300426   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM50300426
PNG
(5-Chloro-2-ethyl-4-methylisothiazol-3(2H)-one | CH...)
Show SMILES CCn1sc(Cl)c(C)c1=O
Show InChI InChI=1S/C6H8ClNOS/c1-3-8-6(9)4(2)5(7)10-8/h3H2,1-2H3
PDB
MMDB

NCI pathway
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KEGG

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



University of Groningen

Curated by ChEMBL


Assay Description
Inhibition of human recombinant histone acetyltransferase PCAF assessed as CoA-SH activity preincubated for 15 mins by CPM fluorescent assay

Eur J Med Chem 44: 4855-61 (2009)


Article DOI: 10.1016/j.ejmech.2009.07.025
BindingDB Entry DOI: 10.7270/Q2XD11RS
More data for this
Ligand-Target Pair