BDBM50300428 CHEMBL574179::cis-2,5-Di(2-benzyl)-pyrrolidine

SMILES: C([C@H]1CC[C@@H](Cc2ccccc2)N1)c1ccccc1

InChI Key: InChIKey=JWFLOEKZECISRU-HDICACEKSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50300428   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vesicular monoamine transporter 2 (VMAT2) (Rattus norvegicus (Rat))	BDBM50300428 (CHEMBL574179 | cis-2,5-Di(2-benzyl)-pyrrolidine) Show SMILES C([C@H]1CC[C@@H](Cc2ccccc2)N1)c1ccccc1 |r| Show InChI InChI=1S/C18H21N/c1-3-7-15(8-4-1)13-17-11-12-18(19-17)14-16-9-5-2-6-10-16/h1-10,17-19H,11-14H2/t17-,18+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Inhibition of [3H]dopamine uptake at VMAT2 in rat brain synaptic vesicle by liquid scintillation spectroscopy				J Med Chem 52: 7878-82 (2009) Article DOI: 10.1021/jm900770h BindingDB Entry DOI: 10.7270/Q25X29V5
					More data for this Ligand-Target Pair
Vesicular monoamine transporter 2 (VMAT2) (Rattus norvegicus (Rat))	BDBM50300428 (CHEMBL574179 | cis-2,5-Di(2-benzyl)-pyrrolidine) Show SMILES C([C@H]1CC[C@@H](Cc2ccccc2)N1)c1ccccc1 |r| Show InChI InChI=1S/C18H21N/c1-3-7-15(8-4-1)13-17-11-12-18(19-17)14-16-9-5-2-6-10-16/h1-10,17-19H,11-14H2/t17-,18+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.64E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Displacement of [3H]DTBZ from VMAT2 dihydrotetrabenazine binding site in rat brain synaptic vesicle by scintillation counting				J Med Chem 52: 7878-82 (2009) Article DOI: 10.1021/jm900770h BindingDB Entry DOI: 10.7270/Q25X29V5
					More data for this Ligand-Target Pair