BDBM50300800 5-(4-Acetylpiperazin-1-yl)pentanoic acid(4-pyridin-3-ylphenyl)amide::CHEMBL578140

SMILES: CC(=O)N1CCN(CCCCC(=O)Nc2ccc(cc2)-c2cccnc2)CC1

InChI Key: InChIKey=SYPFXORROFBXRL-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50300800   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor (Rattus norvegicus (Rat))	BDBM50300800 (5-(4-Acetylpiperazin-1-yl)pentanoic acid(4-pyridin...) Show SMILES CC(=O)N1CCN(CCCCC(=O)Nc2ccc(cc2)-c2cccnc2)CC1 Show InChI InChI=1S/C22H28N4O2/c1-18(27)26-15-13-25(14-16-26)12-3-2-6-22(28)24-21-9-7-19(8-10-21)20-5-4-11-23-17-20/h4-5,7-11,17H,2-3,6,12-16H2,1H3,(H,24,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.78E+3	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Agonist activity at rat alpha7 nAChR expressed in rat GH4C1 cells assessed as calcium flux by FLIPR assay				Bioorg Med Chem 17: 5247-58 (2009) Article DOI: 10.1016/j.bmc.2009.05.040 BindingDB Entry DOI: 10.7270/Q29K4B8H
					More data for this Ligand-Target Pair