BDBM50300804 4-Nitro-N-{4-[4-(2,4-dimethoxyphenyl)piperazin-1-yl]butyl}benzamide::CHEMBL565962

SMILES: COc1ccc(N2CCN(CCCCNC(=O)c3ccc(cc3)[N+]([O-])=O)CC2)c(OC)c1

InChI Key: InChIKey=MHWHIBSVOPCJKK-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50300804   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor (Rattus norvegicus (Rat))	BDBM50300804 (4-Nitro-N-{4-[4-(2,4-dimethoxyphenyl)piperazin-1-y...) Show SMILES COc1ccc(N2CCN(CCCCNC(=O)c3ccc(cc3)[N+]([O-])=O)CC2)c(OC)c1 Show InChI InChI=1S/C23H30N4O5/c1-31-20-9-10-21(22(17-20)32-2)26-15-13-25(14-16-26)12-4-3-11-24-23(28)18-5-7-19(8-6-18)27(29)30/h5-10,17H,3-4,11-16H2,1-2H3,(H,24,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Agonist activity at rat alpha7 nAChR expressed in rat GH4C1 cells assessed as calcium flux by FLIPR assay				Bioorg Med Chem 17: 5247-58 (2009) Article DOI: 10.1016/j.bmc.2009.05.040 BindingDB Entry DOI: 10.7270/Q29K4B8H
					More data for this Ligand-Target Pair