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SMILES: O=C(CCCCN1CCCCC1)Nc1ccc(cc1)-c1ccc2OCOc2c1

InChI Key: InChIKey=POVFNDGJQZYVGH-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50300817   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuronal acetylcholine receptor subunit alpha-7


(Rattus norvegicus (Rat))		BDBM50300817
PNG
(5-Piperidin-1-yl-pentanoic acid benzo[1,3]dioxol-5...)
Show SMILES O=C(CCCCN1CCCCC1)Nc1ccc(cc1)-c1ccc2OCOc2c1
Show InChI InChI=1S/C23H28N2O3/c26-23(6-2-5-15-25-13-3-1-4-14-25)24-20-10-7-18(8-11-20)19-9-12-21-22(16-19)28-17-27-21/h7-12,16H,1-6,13-15,17H2,(H,24,26)
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PC cid
PC sid
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Article
PubMed
n/an/an/an/a 1.09E+4n/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Agonist activity at rat alpha7 nAChR expressed in rat GH4C1 cells assessed as calcium flux by FLIPR assay

Bioorg Med Chem 17: 5247-58 (2009)


Article DOI: 10.1016/j.bmc.2009.05.040
BindingDB Entry DOI: 10.7270/Q29K4B8H
More data for this
Ligand-Target Pair