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SMILES: O=C(CCCCN1CCCCC1)Nc1ccc(cc1)-c1ccc2ncccc2c1

InChI Key: InChIKey=KURCLQHUDFYECP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50300818   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuronal acetylcholine receptor subunit alpha-7


(Rattus norvegicus (Rat))		BDBM50300818
PNG
(5-Piperidin-1-yl-pentanoic acid quinolin-6-ylamide...)
Show SMILES O=C(CCCCN1CCCCC1)Nc1ccc(cc1)-c1ccc2ncccc2c1
Show InChI InChI=1S/C25H29N3O/c29-25(8-2-5-18-28-16-3-1-4-17-28)27-23-12-9-20(10-13-23)21-11-14-24-22(19-21)7-6-15-26-24/h6-7,9-15,19H,1-5,8,16-18H2,(H,27,29)
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Article
PubMed
n/an/an/an/a 5.07E+3n/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Agonist activity at rat alpha7 nAChR expressed in rat GH4C1 cells assessed as calcium flux by FLIPR assay

Bioorg Med Chem 17: 5247-58 (2009)


Article DOI: 10.1016/j.bmc.2009.05.040
BindingDB Entry DOI: 10.7270/Q29K4B8H
More data for this
Ligand-Target Pair