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SMILES: Brc1ccc(cc1)-c1ccc(NC(=O)CCCCN2CCCCC2)cc1

InChI Key: InChIKey=HKUIEWKXWIYDEY-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50300819   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuronal acetylcholine receptor subunit alpha-7


(Rattus norvegicus (Rat))		BDBM50300819
PNG
(5-Piperidin-1-yl-pentanoic acid(4-bromophenyl)amid...)
Show SMILES Brc1ccc(cc1)-c1ccc(NC(=O)CCCCN2CCCCC2)cc1
Show InChI InChI=1S/C22H27BrN2O/c23-20-11-7-18(8-12-20)19-9-13-21(14-10-19)24-22(26)6-2-5-17-25-15-3-1-4-16-25/h7-14H,1-6,15-17H2,(H,24,26)
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Article
PubMed
n/an/an/an/a 1.35E+3n/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Agonist activity at rat alpha7 nAChR expressed in rat GH4C1 cells assessed as calcium flux by FLIPR assay

Bioorg Med Chem 17: 5247-58 (2009)


Article DOI: 10.1016/j.bmc.2009.05.040
BindingDB Entry DOI: 10.7270/Q29K4B8H
More data for this
Ligand-Target Pair