BDBM50300842 CHEMBL565724::N-(2-{3-[(6-Chloroimidazo[2,1-b][1,3]thiazol-5-yl)sulfonyl]-1H-pyrrolo[2,3-b]pyridin-1-yl}ethyl)-N,Ndimethylamine

SMILES: CN(C)CCn1cc(c2cccnc12)S(=O)(=O)c1c(Cl)nc2sccn12

InChI Key: InChIKey=KMZGKMVOTSNHID-UHFFFAOYSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50300842   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50300842 (CHEMBL565724 | N-(2-{3-[(6-Chloroimidazo[2,1-b][1,...) Show SMILES CN(C)CCn1cc(c2cccnc12)S(=O)(=O)c1c(Cl)nc2sccn12 Show InChI InChI=1S/C16H16ClN5O2S2/c1-20(2)6-7-21-10-12(11-4-3-5-18-14(11)21)26(23,24)15-13(17)19-16-22(15)8-9-25-16/h3-5,8-10H,6-7H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cells				Bioorg Med Chem 17: 5153-63 (2009) Article DOI: 10.1016/j.bmc.2009.05.055 BindingDB Entry DOI: 10.7270/Q25T3KJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50300842 (CHEMBL565724 | N-(2-{3-[(6-Chloroimidazo[2,1-b][1,...) Show SMILES CN(C)CCn1cc(c2cccnc12)S(=O)(=O)c1c(Cl)nc2sccn12 Show InChI InChI=1S/C16H16ClN5O2S2/c1-20(2)6-7-21-10-12(11-4-3-5-18-14(11)21)26(23,24)15-13(17)19-16-22(15)8-9-25-16/h3-5,8-10H,6-7H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	120	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Agonist activity at human cloned 5HT6 receptor expressed in HeLa cells assessed as induction of adenylyl cyclase activity by RIA				Bioorg Med Chem 17: 5153-63 (2009) Article DOI: 10.1016/j.bmc.2009.05.055 BindingDB Entry DOI: 10.7270/Q25T3KJS
					More data for this Ligand-Target Pair