BDBM50300890 2-(4-fluorophenyl)-N-(4-(3-(4-fluorophenyl)-5-isopropylisoxazol-4-yl)pyridin-2-yl)acetamide::CHEMBL569151

SMILES: CC(C)c1onc(c1-c1ccnc(NC(=O)Cc2ccc(F)cc2)c1)-c1ccc(F)cc1

InChI Key: InChIKey=MIZDPIXJCBYSCW-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50300890   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50300890 (2-(4-fluorophenyl)-N-(4-(3-(4-fluorophenyl)-5-isop...) Show SMILES CC(C)c1onc(c1-c1ccnc(NC(=O)Cc2ccc(F)cc2)c1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H21F2N3O2/c1-15(2)25-23(24(30-32-25)17-5-9-20(27)10-6-17)18-11-12-28-21(14-18)29-22(31)13-16-3-7-19(26)8-4-16/h3-12,14-15H,13H2,1-2H3,(H,28,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.56E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Curated by ChEMBL					Assay Description Inhibition of p38alpha by Cherenkov counting				J Med Chem 52: 7618-30 (2009) Article DOI: 10.1021/jm9005127 BindingDB Entry DOI: 10.7270/Q28K7961
					More data for this Ligand-Target Pair
Casein kinase I delta (Rattus norvegicus (rat))	BDBM50300890 (2-(4-fluorophenyl)-N-(4-(3-(4-fluorophenyl)-5-isop...) Show SMILES CC(C)c1onc(c1-c1ccnc(NC(=O)Cc2ccc(F)cc2)c1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H21F2N3O2/c1-15(2)25-23(24(30-32-25)17-5-9-20(27)10-6-17)18-11-12-28-21(14-18)29-22(31)13-16-3-7-19(26)8-4-16/h3-12,14-15H,13H2,1-2H3,(H,28,29,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Curated by ChEMBL					Assay Description Inhibition of GST-fused rat CK1delta by Cherenkov counting in presence of 20 uM ATP				J Med Chem 52: 7618-30 (2009) Article DOI: 10.1021/jm9005127 BindingDB Entry DOI: 10.7270/Q28K7961
					More data for this Ligand-Target Pair
Casein kinase I isoform delta (Homo sapiens (Human))	BDBM50300890 (2-(4-fluorophenyl)-N-(4-(3-(4-fluorophenyl)-5-isop...) Show SMILES CC(C)c1onc(c1-c1ccnc(NC(=O)Cc2ccc(F)cc2)c1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H21F2N3O2/c1-15(2)25-23(24(30-32-25)17-5-9-20(27)10-6-17)18-11-12-28-21(14-18)29-22(31)13-16-3-7-19(26)8-4-16/h3-12,14-15H,13H2,1-2H3,(H,28,29,31)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Curated by ChEMBL					Assay Description Inhibition of recombinant CK1delta kinase domain by Cherenkov counting				J Med Chem 52: 7618-30 (2009) Article DOI: 10.1021/jm9005127 BindingDB Entry DOI: 10.7270/Q28K7961
					More data for this Ligand-Target Pair