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SMILES: Cc1ccc(CNc2nc(N)nc(n2)-c2ccc(C[C@H](N)C(O)=O)cc2)cc1C

InChI Key: InChIKey=HRGWGSMDYZDGGF-KRWDZBQOSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50300925   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tryptophan 5-hydroxylase 1


(Homo sapiens (Human))		BDBM50300925
PNG
((S)-2-amino-3-(4-(4-amino-6-(3,4-dimethylbenzylami...)
Show SMILES Cc1ccc(CNc2nc(N)nc(n2)-c2ccc(C[C@H](N)C(O)=O)cc2)cc1C |r|
Show InChI InChI=1S/C21H24N6O2/c1-12-3-4-15(9-13(12)2)11-24-21-26-18(25-20(23)27-21)16-7-5-14(6-8-16)10-17(22)19(28)29/h3-9,17H,10-11,22H2,1-2H3,(H,28,29)(H3,23,24,25,26,27)/t17-/m0/s1
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Princ

Curated by ChEMBL


Assay Description
Inhibition of human recombinant TPH1 by continuous fluorescence assay

Bioorg Med Chem Lett 19: 5229-32 (2009)


Article DOI: 10.1016/j.bmcl.2009.07.005
BindingDB Entry DOI: 10.7270/Q2MS3SV0
More data for this
Ligand-Target Pair