BDBM50301115 (3S,5S,6S)-5-(hydroxycarbamoyl)-1-methyl-6-(4-phenylpiperazine-1-carbonyl)piperidin-3-yl dimethylcarbamate::CHEMBL567940

SMILES: CN(C)C(=O)O[C@H]1C[C@@H]([C@H](N(C)C1)C(=O)N1CCN(CC1)c1ccccc1)C(=O)NO

InChI Key: InChIKey=VPNMZNYQFRFELQ-BZSNNMDCSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50301115   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Disintegrin and metalloproteinase domain-containing protein 10 (ADAM10) (Homo sapiens (Human))	BDBM50301115 ((3S,5S,6S)-5-(hydroxycarbamoyl)-1-methyl-6-(4-phen...) Show SMILES CN(C)C(=O)O[C@H]1C[C@@H]([C@H](N(C)C1)C(=O)N1CCN(CC1)c1ccccc1)C(=O)NO |r| Show InChI InChI=1S/C21H31N5O5/c1-23(2)21(29)31-16-13-17(19(27)22-30)18(24(3)14-16)20(28)26-11-9-25(10-12-26)15-7-5-4-6-8-15/h4-8,16-18,30H,9-14H2,1-3H3,(H,22,27)/t16-,17-,18-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation Curated by ChEMBL					Assay Description Inhibition of ADAM-10				Bioorg Med Chem Lett 19: 5037-42 (2009) Article DOI: 10.1016/j.bmcl.2009.07.052 BindingDB Entry DOI: 10.7270/Q2154J0S
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50301115 ((3S,5S,6S)-5-(hydroxycarbamoyl)-1-methyl-6-(4-phen...) Show SMILES CN(C)C(=O)O[C@H]1C[C@@H]([C@H](N(C)C1)C(=O)N1CCN(CC1)c1ccccc1)C(=O)NO |r| Show InChI InChI=1S/C21H31N5O5/c1-23(2)21(29)31-16-13-17(19(27)22-30)18(24(3)14-16)20(28)26-11-9-25(10-12-26)15-7-5-4-6-8-15/h4-8,16-18,30H,9-14H2,1-3H3,(H,22,27)/t16-,17-,18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation Curated by ChEMBL					Assay Description Inhibition of MMP-2				Bioorg Med Chem Lett 19: 5037-42 (2009) Article DOI: 10.1016/j.bmcl.2009.07.052 BindingDB Entry DOI: 10.7270/Q2154J0S
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50301115 ((3S,5S,6S)-5-(hydroxycarbamoyl)-1-methyl-6-(4-phen...) Show SMILES CN(C)C(=O)O[C@H]1C[C@@H]([C@H](N(C)C1)C(=O)N1CCN(CC1)c1ccccc1)C(=O)NO |r| Show InChI InChI=1S/C21H31N5O5/c1-23(2)21(29)31-16-13-17(19(27)22-30)18(24(3)14-16)20(28)26-11-9-25(10-12-26)15-7-5-4-6-8-15/h4-8,16-18,30H,9-14H2,1-3H3,(H,22,27)/t16-,17-,18-/m0/s1	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation Curated by ChEMBL					Assay Description Inhibition of HER-2				Bioorg Med Chem Lett 19: 5037-42 (2009) Article DOI: 10.1016/j.bmcl.2009.07.052 BindingDB Entry DOI: 10.7270/Q2154J0S
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50301115 ((3S,5S,6S)-5-(hydroxycarbamoyl)-1-methyl-6-(4-phen...) Show SMILES CN(C)C(=O)O[C@H]1C[C@@H]([C@H](N(C)C1)C(=O)N1CCN(CC1)c1ccccc1)C(=O)NO |r| Show InChI InChI=1S/C21H31N5O5/c1-23(2)21(29)31-16-13-17(19(27)22-30)18(24(3)14-16)20(28)26-11-9-25(10-12-26)15-7-5-4-6-8-15/h4-8,16-18,30H,9-14H2,1-3H3,(H,22,27)/t16-,17-,18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation Curated by ChEMBL					Assay Description Inhibition of MMP-3				Bioorg Med Chem Lett 19: 5037-42 (2009) Article DOI: 10.1016/j.bmcl.2009.07.052 BindingDB Entry DOI: 10.7270/Q2154J0S
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50301115 ((3S,5S,6S)-5-(hydroxycarbamoyl)-1-methyl-6-(4-phen...) Show SMILES CN(C)C(=O)O[C@H]1C[C@@H]([C@H](N(C)C1)C(=O)N1CCN(CC1)c1ccccc1)C(=O)NO |r| Show InChI InChI=1S/C21H31N5O5/c1-23(2)21(29)31-16-13-17(19(27)22-30)18(24(3)14-16)20(28)26-11-9-25(10-12-26)15-7-5-4-6-8-15/h4-8,16-18,30H,9-14H2,1-3H3,(H,22,27)/t16-,17-,18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation Curated by ChEMBL					Assay Description Inhibition of MMP-9				Bioorg Med Chem Lett 19: 5037-42 (2009) Article DOI: 10.1016/j.bmcl.2009.07.052 BindingDB Entry DOI: 10.7270/Q2154J0S
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50301115 ((3S,5S,6S)-5-(hydroxycarbamoyl)-1-methyl-6-(4-phen...) Show SMILES CN(C)C(=O)O[C@H]1C[C@@H]([C@H](N(C)C1)C(=O)N1CCN(CC1)c1ccccc1)C(=O)NO |r| Show InChI InChI=1S/C21H31N5O5/c1-23(2)21(29)31-16-13-17(19(27)22-30)18(24(3)14-16)20(28)26-11-9-25(10-12-26)15-7-5-4-6-8-15/h4-8,16-18,30H,9-14H2,1-3H3,(H,22,27)/t16-,17-,18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation Curated by ChEMBL					Assay Description Inhibition of MMP-1				Bioorg Med Chem Lett 19: 5037-42 (2009) Article DOI: 10.1016/j.bmcl.2009.07.052 BindingDB Entry DOI: 10.7270/Q2154J0S
					More data for this Ligand-Target Pair