BDBM50301122 (2S,3S)-N-hydroxy-5-(N-methylisobutyramido)-2-((R)-3-phenylpyrrolidine-1-carbonyl)piperidine-3-carboxamide::CHEMBL567939

SMILES: CC(C)C(=O)N(C)C1CN[C@@H]([C@H](C1)C(=O)NO)C(=O)N1CC[C@@H](C1)c1ccccc1

InChI Key: InChIKey=OKGOBXODUWTHAJ-RNLLHNEJSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50301122   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50301122 ((2S,3S)-N-hydroxy-5-(N-methylisobutyramido)-2-((R)...) Show SMILES CC(C)C(=O)N(C)C1CN[C@@H]([C@H](C1)C(=O)NO)C(=O)N1CC[C@@H](C1)c1ccccc1 |r| Show InChI InChI=1S/C22H32N4O4/c1-14(2)21(28)25(3)17-11-18(20(27)24-30)19(23-12-17)22(29)26-10-9-16(13-26)15-7-5-4-6-8-15/h4-8,14,16-19,23,30H,9-13H2,1-3H3,(H,24,27)/t16-,17?,18-,19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	502	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation Curated by ChEMBL					Assay Description Inhibition of MMP-2				Bioorg Med Chem Lett 19: 5037-42 (2009) Article DOI: 10.1016/j.bmcl.2009.07.052 BindingDB Entry DOI: 10.7270/Q2154J0S
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 10 (ADAM10) (Homo sapiens (Human))	BDBM50301122 ((2S,3S)-N-hydroxy-5-(N-methylisobutyramido)-2-((R)...) Show SMILES CC(C)C(=O)N(C)C1CN[C@@H]([C@H](C1)C(=O)NO)C(=O)N1CC[C@@H](C1)c1ccccc1 |r| Show InChI InChI=1S/C22H32N4O4/c1-14(2)21(28)25(3)17-11-18(20(27)24-30)19(23-12-17)22(29)26-10-9-16(13-26)15-7-5-4-6-8-15/h4-8,14,16-19,23,30H,9-13H2,1-3H3,(H,24,27)/t16-,17?,18-,19-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	138	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation Curated by ChEMBL					Assay Description Inhibition of ADAM-10				Bioorg Med Chem Lett 19: 5037-42 (2009) Article DOI: 10.1016/j.bmcl.2009.07.052 BindingDB Entry DOI: 10.7270/Q2154J0S
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50301122 ((2S,3S)-N-hydroxy-5-(N-methylisobutyramido)-2-((R)...) Show SMILES CC(C)C(=O)N(C)C1CN[C@@H]([C@H](C1)C(=O)NO)C(=O)N1CC[C@@H](C1)c1ccccc1 |r| Show InChI InChI=1S/C22H32N4O4/c1-14(2)21(28)25(3)17-11-18(20(27)24-30)19(23-12-17)22(29)26-10-9-16(13-26)15-7-5-4-6-8-15/h4-8,14,16-19,23,30H,9-13H2,1-3H3,(H,24,27)/t16-,17?,18-,19-/m0/s1	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation Curated by ChEMBL					Assay Description Inhibition of HER-2				Bioorg Med Chem Lett 19: 5037-42 (2009) Article DOI: 10.1016/j.bmcl.2009.07.052 BindingDB Entry DOI: 10.7270/Q2154J0S
					More data for this Ligand-Target Pair