Found 3 hits for monomerid = 50301123 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50301123
((2S,3S)-N-hydroxy-5-(N-methylbenzamido)-2-((R)-3-p...)Show SMILES CN(C1CN[C@@H]([C@H](C1)C(=O)NO)C(=O)N1CC[C@@H](C1)c1ccccc1)C(=O)c1ccccc1 |r| Show InChI InChI=1S/C25H30N4O4/c1-28(24(31)18-10-6-3-7-11-18)20-14-21(23(30)27-33)22(26-15-20)25(32)29-13-12-19(16-29)17-8-4-2-5-9-17/h2-11,19-22,26,33H,12-16H2,1H3,(H,27,30)/t19-,20?,21-,22-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
Incyte Corporation
Curated by ChEMBL
| Assay Description Inhibition of MMP-2 |
Bioorg Med Chem Lett 19: 5037-42 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.052 BindingDB Entry DOI: 10.7270/Q2154J0S |
More data for this Ligand-Target Pair | |
Disintegrin and metalloproteinase domain-containing protein 10 (ADAM10)
(Homo sapiens (Human)) | BDBM50301123
((2S,3S)-N-hydroxy-5-(N-methylbenzamido)-2-((R)-3-p...)Show SMILES CN(C1CN[C@@H]([C@H](C1)C(=O)NO)C(=O)N1CC[C@@H](C1)c1ccccc1)C(=O)c1ccccc1 |r| Show InChI InChI=1S/C25H30N4O4/c1-28(24(31)18-10-6-3-7-11-18)20-14-21(23(30)27-33)22(26-15-20)25(32)29-13-12-19(16-29)17-8-4-2-5-9-17/h2-11,19-22,26,33H,12-16H2,1H3,(H,27,30)/t19-,20?,21-,22-/m0/s1 | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 84 | n/a | n/a | n/a | n/a | n/a | n/a |
Incyte Corporation
Curated by ChEMBL
| Assay Description Inhibition of ADAM-10 |
Bioorg Med Chem Lett 19: 5037-42 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.052 BindingDB Entry DOI: 10.7270/Q2154J0S |
More data for this Ligand-Target Pair | |
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human)) | BDBM50301123
((2S,3S)-N-hydroxy-5-(N-methylbenzamido)-2-((R)-3-p...)Show SMILES CN(C1CN[C@@H]([C@H](C1)C(=O)NO)C(=O)N1CC[C@@H](C1)c1ccccc1)C(=O)c1ccccc1 |r| Show InChI InChI=1S/C25H30N4O4/c1-28(24(31)18-10-6-3-7-11-18)20-14-21(23(30)27-33)22(26-15-20)25(32)29-13-12-19(16-29)17-8-4-2-5-9-17/h2-11,19-22,26,33H,12-16H2,1H3,(H,27,30)/t19-,20?,21-,22-/m0/s1 | PDB MMDB
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
Incyte Corporation
Curated by ChEMBL
| Assay Description Inhibition of HER-2 |
Bioorg Med Chem Lett 19: 5037-42 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.052 BindingDB Entry DOI: 10.7270/Q2154J0S |
More data for this Ligand-Target Pair | |